The Google Play Store appears to be down for users in Puerto Rico. A thread over at the Android section of the Google Code site has received lots of responses from people in Puerto Rico confirming the issue. The problem is affecting a variety of handsets, including the Motorola Xoom (pictured above) to the Galaxy Nexus.
If you're in Puerto Rico and are also experiencing the issue, please head over and report it to Google. Make sure to tell them which device you have and what version of Android you're running.
Hopefully this issue can be quickly resolved.
Source: Google Code
Image courtesy of gcolon