Some folks want BlinkFeed -- HTC's home screen news reader -- to die in a fire. They don't like the idea of BlinkFeed. They think it's a bad idea (never mind not having actually used it), and they don't ever want to see it.
We can grant that wish.
It's perfectly possible to use the HTC One without BlinkFeed being in the way.
The secret? Just don't use it.
You don't actually have to set up BlinkFeed. You can ignore it to your heart's content. It won't use data. It won't use your battery. And it won't be in the way.
The trick is to set up your home screens like normal and just never thumb all the way to the left to the BlinkFeed screen. OK, that's not much of a trick. Out of sight, out of mind.
Or, of course, you could just use a custom launcher, which a good many folks likely will do anyway.
Chances are someone will hack BlinkFeed out of Sense 5 while leaving the rest of the ROM intact. And that's cool. But that's also more work than not actually using BlinkFeed in the first place.
The bottom line is if you don't want to use BlinkFeed, you don't have to. And it's not at all in the way.